Search results for "Standard Preparations"

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Implementation and microbiological stability of dose-banded ganciclovir infusion bags prepared in series by a robotic system.

2018

Objectives The implementation of dose-banding (DB) in centralised, pharmacy-based cytotoxic drug preparation units allows the preparation of standardised doses in series. The aim of this study was to evaluate the feasibility of DB for the prescribing of ganciclovir (GV) infusion solutions and to investigate the microbiological stability of dose-banded, automatically prepared ready-to-administer GV infusion bags by media-fill simulation tests and sterility tests. Methods The frequency of prescription of GV doses was retrospectively analysed before and after implementing the DB scheme. Four dose-ranges or ‘bands’ and the corresponding standard doses (250, 300, 350, 400 mg) were identified. Th…

GanciclovirCytotoxic drugSterilityDrug CompoundingDrug StorageGrowth promotion030226 pharmacology & pharmacyAntiviral AgentsStandard PreparationsExtended storage03 medical and health sciences0302 clinical medicineAnimal scienceDrug StabilityRefrigerationMedicineInfusions Parenteral030212 general & internal medicineGeneral Pharmacology Toxicology and PharmaceuticsGanciclovirDrug PackagingRetrospective StudiesOriginal Researchbusiness.industryReproducibility of ResultsRoboticsRobotic systemsAseptic processingbusinessDrug ContaminationPharmacy Service Hospitalmedicine.drugEuropean journal of hospital pharmacy : science and practice
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